Role of nuclear receptor pxr in immune cells and inflammatory diseases

HIGHLIGHTS

  • who: Le Sun from the Autonomous University of Madrid, Spain have published the paper: Role of nuclear receptor PXR in immune cells and inflammatory diseases, in the Journal: (JOURNAL)
  • future: The effect of PXR on IBD pathogenesis is sophisticated and more investigations are needed to further illuminate its novel functions and potential molecular mechanisms.

SUMMARY

    Pregnane X receptor (PXR) is a member of the nuclear receptor superfamily with highly conserved structures, that have an activation domain (AF), a central DNA-binding domain (DBD), a hinge region, a ligand-binding domain (LBD . . .

     

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