Circulating tumor dna sequencing provides comprehensive mutation profiling for pediatric central nervous system tumors

HIGHLIGHTS

• who: Erin R. Bonner from the Published in partnership with The Hormel Institute, University of Minnesota have published the article: Circulating tumor DNA sequencing provides comprehensive mutation profiling for pediatric central nervous system tumors, in the Journal: (JOURNAL)
• what: To evaluate the clinical utility of the platform , the authors focused on CSF collected at upfront diagnosis or during the course of treatment (IDs 933, 1549).
• how: The authors compared these results to the ddPCR -based H3K27M assay67 using eight paired liquid specimens and detected similar H3K27M variant allele frequencies (VAF) using both approaches . . .
  

   

  

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