Opioid use disorder and alternative mrna splicing in reward circuitry

HIGHLIGHTS

• who: Spencer B. Huggett and collaborators from the Behavioral Genetics of Addiction Laboratory, Department of Psychology at Emory University have published the paper: Opioid Use Disorder and Alternative mRNA Splicing in Reward Circuitry, in the Journal: Genes of 22/Nov/2021
• what: Using publicly available RNA-sequencing data the study investigated the possible role of alternative mRNA splicing in human brain tissue (dorsal-lateral prefrontal cortex (dlPFC) nucleus accumbens (NAc) and midbrain) of 90 individuals with OUD or matched controls. Building on previous studies, the authors show that spliceosome genes tend to be upregulated in . . .
  

   

  

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