HIGHLIGHTS
- who: Guillaume Taieb and collaborators from the University of Erlangen Nuremberg, Germany have published the article: Effect of monovalency on anti-contactin-1 IgG4, in the Journal: (JOURNAL)
- what: Of course, this study has several limitations.
SUMMARY
The proportion of monospecific/bispecific anti-CNTN1 antibodies was estimated in each patient by ELISA by examining the ability of serum antibodies to cross-link untagged CNTN1 with biotinylated CNTN1. To determine the impact of monovalency, anti-CNTN1 IgG4 were enzymatically digested into monovalent Fab and tested in_vitro on cell aggregation assay. Native anti . . .
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