Phosphorylation of phf2 by ampk releases the repressive h3k9me2 and inhibits cancer metastasis

HIGHLIGHTS

  • who: Ying Dong from the (UNIVERSITY) have published the Article: Phosphorylation of PHF2 by AMPK releases the repressive H3K9me2 and inhibits cancer metastasis, in the Journal: (JOURNAL) of 30/05/2022
  • what: AMPK activation inhibits lung cancer metastasis and releases the repressive H3K9me2 mark on epithelial genes To better define the epigenetic regulatory role of AMPK in cancer metastasis, the authors intended to focus on investigating AMPKu03b12 subunit which prefers nuclear localization than AMPKu03b11.19 As shown in the results above, CDH1 was upregulated by metformin in transcriptional and protein levels, thus the authors intended . . .

     

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