Repeated truncation of a modular antimicrobial peptide gene for neural context

HIGHLIGHTS

SUMMARY

    AMPs and AMP-like genes in many species have recently been implicated in non-immune roles in flies, nematodes, and humans, suggesting non-immune functions might help explain AMP evolutionary patterns. BaraA mutants are susceptible to infection by fungi, and in_vitro experiments suggest the BaraA IM10-like peptides have antifungal activity Repeated truncation of a modular antimicrobial peptide gene for neural context. Both BaraB and BaraC have truncations compared to the ancestral Baramicin gene, and these two genes effectively encode just the Baramicin IM24 domain. The authors will therefore first provide a basic description . . .

     

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