Synthesis and biological activity evaluation of 2-cyanopyrrole derivatives as potential tyrosinase inhibitors

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  • who: Hu Y-G and collaborators from the School of Pharmacy and State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou, China, School of have published the Article: Synthesis and Biological Activity Evaluation of 2-Cyanopyrrole Derivatives as Potential Tyrosinase Inhibitors, in the Journal: (JOURNAL)
  • how: These results indicated that the introduction of fluorine bromine methoxy and trifluoromethyl alone might cause a decrease in tyrosinase inhibitory activity. These results indicated that the cyano group of compounds A1-A17 was crucial for tyrosinase inhibition. passed through the origin point. The results were analyzed using Lineweaver . . .

     

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