Amyloid-β impairs mitochondrial dynamics and autophagy in alzheimer’s disease experimental models

HIGHLIGHTS

  • who: Macarena de la Cueva from the Network Center forUniversidad Autu00f3noma de have published the Article: Amyloid-u03b2 impairs mitochondrial dynamics and autophagy in Alzheimeru2019s disease experimental models, in the Journal: Scientific Reports Scientific Reports of 22/09/2010
  • what: The analysis showed that Au03b242 incubation increased mitophagy as demonstrated the increase of autophagy markers colocalising with the mitochondria (Manders` coefficients for p62 and CxVu03b2: untreated cells, M1=1, M2=0.89; cells with Au03b242, M1=1, M2=0.97; Manders` coefficients for LC3-II and CxVu03b2: untreated cells, M1=1, M2=0.89; cells . . .

     

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