Map4k4/jnk signaling pathway stimulates proliferation and suppresses apoptosis of human spermatogonial stem cells and lower level of map4k4 is associated with male infertility

HIGHLIGHTS

• who: Cailin Wan et al. from the The Key Laboratory of Model Animals and Stem Cell Biology in Hunan Province, Hunan Normal University Reproductive Health New Technology of Hunan Normal University, Changsha, China have published the research: MAP4K4/JNK Signaling Pathway Stimulates Proliferation and Suppresses Apoptosis of Human Spermatogonial Stem Cells and Lower Level of MAP4K4 Is Associated with Male Infertility, in the Journal: Cells 2022, 11, 3807. of /2022/
• what: The authors have demonstrated that MAP4K4 was predominantly expressed in human UCHL1-positive spermatogonia by double immunocytochemical staining. Collectively, this study provides novel insights . . .
  

   

  

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