Ddb2 represses epithelial-to-mesenchymal transition and sensitizes pancreatic ductal adenocarcinoma cells to chemotherapy

HIGHLIGHTS

  • who: Julie Dardare from the Laboratory of Biosciences (IRCCS), Italy Cornell University, United States have published the research: DDB2 represses epithelial-to-mesenchymal transition and sensitizes pancreatic ductal adenocarcinoma cells to chemotherapy, in the Journal: (JOURNAL)
  • what: The authors show that DDB2 can repress EMT, migration and invasion in PDAC cell models. The authors evaluated the role of DDB2 in the response of PDAC cell lines to conventional chemotherapies used for the management of patients with PDAC. The authors reported that DDB2 protein expression level was found lower in PDAC tissues from different stages and . . .

     

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