Nonviral sepsis

HIGHLIGHTS

• who: IFITM et al. from the University of of Medicine, Intermountain Medical Center, Murray, Utah, USA have published the Article: nonviral sepsis, in the Journal: (JOURNAL)
• how: To then establish the necessity of IFITM3 for IFN-dependent increase in fibrinogen uptake the authors employed shRNA to specifically knock down IFITM3 only in MEG-01s while preserving the expression of IFITM1 and IFITM2. To determine whether there was a relevant in_vivo function for the upregulation of platelet IFITM3 the authors utilized 2 platelet-dependent thrombosis models .
• future: Interestingly platelets from patients with multiple myeloma . . .
  

   

  

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