Identification of hepatocellular carcinoma subtypes based on pcg-related genes and biological relevance with cancer cells

HIGHLIGHTS

  • who: Yunong Fu from the Department of Hepatobiliary Surgery, The First Affiliated Hospital of Xiu2019an Jiaotong University, Xiu2019an, Shaanxi, China have published the research work: Identification of hepatocellular carcinoma subtypes based on PcG-related genes and biological relevance with cancer cells, in the Journal: (JOURNAL)
  • what: Contributions: the study provided a novel molecular classification system based on PcG-related genes data and experimentally validated the biological features of HCC in two subgroups. The authors focused on H3K27me3 and H2AK119ub, which are regulated by PcG complexes and found these histone modifications have a broad influence on . . .

     

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