The role of triggering receptor expressed on myeloid cells-1 (trem-1) in central nervous system diseases

HIGHLIGHTS

• who: Chunyan Zhang from the (UNIVERSITY) have published the research work: The role of triggering receptor expressed on myeloid cells-1 (TREM-1) in central nervous system diseases, in the Journal: (JOURNAL)
• what: The authors provide a general overview of the structure, expression and physiological function of TREM-1 signaling and its role in different neurological disorders. This study shows that crosstalk exists between TREM-1 and TLR4 pathways, which jointly promote inflammation and exacerbate EBI.
• how: The same results were obtained in LPS-stimulated astrocytes and BV2 cells by transfection with TREM . . .
  

   

  

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