HIGHLIGHTS
- who: Leorey N. Saligan from the National Institute of Nursing Research, National Institutes of Health, Bethesda, MD, United States University of Cincinnati, United States have published the article: BDNF Val66Met Polymorphism Reduces the Fatigue-Like Effects of 5-Fluorouracil on Voluntary Wheel-Running Activity in Mice, in the Journal: (JOURNAL)
- what: The authors used a mouse model to test whether mice with the Val66Met polymorphism are protected from fatigue-like effects of the commonly used chemotherapy drug, 5-fluororuracil (5FU), and assess whether age and sex played a role in modulating this effect.
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