The role and mechanism of lysine methyltransferase and arginine methyltransferase in kidney diseases

HIGHLIGHTS

  • who: Methyltransferase et al. from the Department of Nephrology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China, Department of have published the research work: The Role and Mechanism of Lysine Methyltransferase and Arginine Methyltransferase in Kidney Diseases, in the Journal: (JOURNAL)

SUMMARY

    Epigenetics refers to heritable changes in gene function and phenotype without altering the gene`s DNA sequence (Berger et_al, 2009). Targeting associated epigenetic factors with small_molecules may provide an effective way to "repair" disordered gene/chromosomal regulatory systems caused by abnormal epigenetic profiles. In recent years, histone methyltransferases have . . .

     

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