HIGHLIGHTS
- who: Marco M. Rodari from the University of Colorado Anschutz Medical Campus, United States have published the paper: Dysregulation of the immune response in TGF-u03b2 signalopathies, in the Journal: (JOURNAL)
- what: The authors provide an overview of the TGF-b signaling pathway .
- future: More work is needed to better elucidate the details of their TGF-b-dependent activation .
SUMMARY
This cytokine orchestrates T lymphocyte regulation by limiting effector T_cell functions and promoting regulatory T_cell development and functions. Binding of one of these cytokines to a TGF-bR2 dimer . . .
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