Exosomes from cisplatin-induced dormant cancer cells facilitate the formation of premetastatic niche in bone marrow through activating glycolysis of bmscs

HIGHLIGHTS

  • who: Jiaqi Xu from the University of Pisa, Italy have published the Article: Exosomes from cisplatin-induced dormant cancer cells facilitate the formation of premetastatic niche in bone marrow through activating glycolysis of BMSCs, in the Journal: (JOURNAL)
  • what: In this study, the effect of dormant lung cancer cell-derived exosomes on the formation of the premetastatic niche in bone marrow was investigated.
  • how: The authors introduced an in_vitro model of tumor dormancy induced by short-term treatment with cisplatin according to previously published protocols . IGF-1R inhibitor BMS-536924 was applied in . . .

     

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