A defect in cell wall recycling confers antibiotic resistance and sensitivity in staphylococcus aureus

HIGHLIGHTS

  • who: Stephanie Tan from the Stephanie Tan, Kelvin Cho, and Justin RNodwell* From the Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada Edited by Chris Whitfield have published the research: A defect in cell wall recycling confers antibiotic resistance and sensitivity in Staphylococcus aureus, in the Journal: (JOURNAL) of July/16,/2022
  • what: The authors show that a T101M mutation in walR confers a defect in autolysis, a thickened cell wall, and decreased susceptibility to antibiotics that target lipid II cycle, a phenotype that is reminiscent of the clinical resistance form known as vancomycin . . .

     

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