Autism npcs from both idiopathic and cnv 16p11.2 deletion patients exhibit dysregulation of proliferation and mitogenic responses

HIGHLIGHTS

• who: Robert Connacher from the Medical School, Piscataway, NJ, USA Rutgers University have published the research: Autism NPCs from both idiopathic and CNV 16p11.2 deletion patients exhibit dysregulation of proliferation and mitogenic responses, in the Journal: (JOURNAL) of June/14,/2022
• what: The authors employed a rigorous approach to assess neurogenesis utilizing 53 NPC derivations from 24 distinct iPSC lines of 10 individuals, to compare the proliferation phenotypes between an idiopathic ASD subgroup and the genetically defined 16pDel model.
• how: For the 16pDel cohort the authors selected from RUCDR Infinite Biologics the . . .
  

   

  

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