HIGHLIGHTS
- who: Zahra Malakoutikhah from the (UNIVERSITY) have published the paper: The dual role of Nrf2 in melanoma: a systematic review, in the Journal: (JOURNAL)
- what: The authors aimed to systematically review all the studies discussing the function of Nrf2 in melanoma and the factors determining its alteration.
SUMMARY
Targeted and immune therapies have improved patient survival in melanoma, chemoresistance prevents improving patients` survival. If antioxidants do not detoxify ROS, the cell will experience a rise in oxidative stress, altering the structure and function of critical cellular macromolecules like DNA, leading to . . .
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