HIGHLIGHTS
- who: Huan Li and colleagues from the The Seventh Affiliated Hospital of Sun Yat-Sen University, Shenzhen, Guangdong, China have published the article: APY0201 Represses Tumor Growth through Inhibiting Autophagy in Gastric Cancer Cells, in the Journal: Journal of Oncology of 24/06/2022
- what: The authors investigate the effect of APY0201 an inhibitor of PIKfyve on GC tumor growth and its mechanism of action. The authors demonstrated that APY0201 blocked autophagic flux and caused autophagosome accumulation in GC cells. This study showed that APY0201 has a significant inhibitory effect on GC cell proliferation.
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