HIGHLIGHTS
- who: Tianyi Zhang from the (UNIVERSITY) have published the Article: Cancer-associated fibroblasts in pancreatic ductal adenocarcinoma, in the Journal: (JOURNAL) of 11/06/2022
- what: The authors focus on SHH and TGF-u03b2 signalling as examples to illustrate the complex relationship between CAFs and tumour cells in PDAC.
- future: The role of metabolism-targeted therapy in CAFs should also be emphasised in future research including the effects on the tumour cells and the modulation of the immune microenvironment. Investigations are required to understand better the functional heterogeneity of CAFs in the TME . . .
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