Patient-derived xenograft models for gastrointestinal tumors: a single-center retrospective study

HIGHLIGHTS

  • who: Xiongfei Yu and collaborators from the of Colorado, United States have published the paper: Patient-derived xenograft models for gastrointestinal tumors: A single-center retrospective study, in the Journal: (JOURNAL)
  • what: The authors analyzed clinical parameters that were associated with the engraftment rate of PDXs from patients with GI cancer to identify factors that could improve Frontiers in Oncology The authors presented two typical patients with KRAS mutations who developed recurrence and distant metastasis after treatments.
  • how: The clinical data were collected from patient records. Based on Amplification Transformation System (ARMS) technology . . .

     

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