HIGHLIGHTS
- who: Paulina Biniecka and collaborators from the Central Laboratory of Hematology, Department of Medical Laboratory and Pathology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland have published the research: Anticancer Activities of Novel Nicotinamide Phosphoribosyltransferase Inhibitors in Hematological Malignancies, in the Journal: Molecules 2023, 28, x FOR PEER REVIEW of 20/01/2023
- what: The authors report the synthesis of new JJ08 and which exhibit a broad anticancer activity in vitro. The authors show that these compounds are potent NAMPT inhibitors that profoundly deplete NAD(H) and NADP(H) after 24 h of incubation . . .
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