Modeling the early stages of alzheimer’s disease by administering intracerebroventricular injections of human native aβ oligomers to rats

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  • who: Eva Baerends from the (UNIVERSITY) have published the article: Modeling the early stages of Alzheimeru2019s disease by administering intracerebroventricular injections of human native Au03b2 oligomers to rats, in the Journal: (JOURNAL)
  • what: Unlike advanced AD the initial steps of AD pathophysiology have been poorly investigated partially due to limited availability of animal models focused on the early plaque-free stages of the disease. The aim of this study was to evaluate the early behavioral anatomical and molecular alterations in wild-type rats following intracerebroventricular injections of human Au03b2 oligomers (Au03b2Os). Acknowledging that this study . . .

     

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