Human slfn5 and its xenopus laevis ortholog regulate entry into mitosis and oocyte meiotic resumption

HIGHLIGHTS

• who: Gianmatteo Vit from the (UNIVERSITY) have published the research: Human SLFN5 and its Xenopus Laevis ortholog regulate entry into mitosis and oocyte meiotic resumption, in the Journal: (JOURNAL) of 24/08/2022
• what: The authors show that SLFN5, which shares a high degree of sequence homology with SLFN11, is ubiquitously expressed in proliferating cells and plays a role in the regulation of the transition from S to G2 phase of the cell cycle. The authors demonstrate that the phosphorylation status of SLFN5 influences PP2A-B55u03b1 binding and normal cellular proliferation. The authors show that . . .
  

   

  

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