Management of children and adolescents with chronic myeloid leukemia in blast phase: international pediatric cml expert panel recommendations

HIGHLIGHTS

• who: Stephanie Sembill from the (UNIVERSITY) have published the research work: Management of children and adolescents with chronic myeloid leukemia in blast phase: International pediatric CML expert panel recommendations, in the Journal: (JOURNAL) of 27/01/2023
• what: This studies demonstrate that most pediatric patients achieve complete cytogenetic remission and a BCR::ABL1 transcript level below 1% after acute leukemia induction chemotherapy with added TKI treatment .
• future: In de novo BP a tyrosine kinase domain mutation analysis should be performed at diagnosis because a resistance-mediating mutation is already present in a large . . .
  

   

  

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