HIGHLIGHTS
- who: Ana Chegu00e3o from the (UNIVERSITY) have published the research: Glycation modulates glutamatergic signaling and exacerbates Parkinsonu2019s disease-like phenotypes, in the Journal: (JOURNAL) of October/16,/2019
- what: The authors aimed to determine whether generalized glycation in the mouse brain could trigger PD-like features, and to identify the molecular pathways implicated in this process. In total, the study provides novel mechanistic insight into the connection between metabolic alterations, as those present in type-2 diabetes_mellitus, and PD, opening novel avenues for the design of therapeutic interventions.
- how: MGO triggers neuronal loss . . .
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