Cyclooxygenase-2 in adipose_tissue macrophages limits adipose_tissue dysfunction in obese mice

HIGHLIGHTS

• who: Yu Pan and collaborators from the DivisionVanderbilt University of Medicine, Nashville, Tennessee, USA have published the research: Cyclooxygenase-2 in adipose_tissue macrophages limits adipose_tissue dysfunction in obese mice, in the Journal: (JOURNAL)
• what: This studies examined the role of COX-2 and the PGE2 receptor, EP4, in mediating ATM recruitment, prolifera1 This studies demonstrated that in response to an HFD, ATMs increased COX-2 expression.
• how: These results indicated that macrophage COX-2-/- adipose_tissue facilitated monocyte recruitment and COX-2-/- monocytes were more responsive to homing cues from the adipose_tissue. For most . . .
  

   

  

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