Zinc transport from the endoplasmic reticulum to the cytoplasm via zip7 is necessary for barrier dysfunction mediated by inflammatory signaling in rpe cells

HIGHLIGHTS

• who: YongYao Xu and collaborators from the Department of Ophthalmology, Novartis Institutes of Biomedical Research, Cambridge, MA, United States ofEditor: Yulia Komarova, University of Illinois at have published the paper: Zinc transport from the endoplasmic reticulum to the cytoplasm via Zip7 is necessary for barrier dysfunction mediated by inflammatory signaling in RPE cells, in the Journal: PLOS ONE of July/28,/2022
• what: The authors show for the first time in RPE cells a role for Zn in the signaling pathways downstream of IL-1 u03b2 /TNF- u03b1 in cytokine induction and in mediating barrier . . .
  

   

  

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