Identification of new purpuroine analogues from the arctic echinodermata pteraster militaris that inhibit flt3-itd+ aml cell lines

HIGHLIGHTS

  • who: Sara Ullsten and colleagues from the Department of Chemistry, UiT-The University of, have published the paper: Identification of New Purpuroine Analogues from the Arctic Echinodermata Pteraster militaris That Inhibit FLT3-ITD+ AML Cell Lines, in the Journal: (JOURNAL)
  • what: This study resulted in the isolation of three, previously not described, co in acute myeloid leukemia (AML).
  • how: Due to previous documentation of antibacterial activity of compounds from the purpuroine family compounds 1-3 were tested in a broad antibacterial antifungal and biofilm formation panel. The three compounds were tested for growth . . .

     

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