Bioprocess development and characterization of a 13c-labeled hybrid bispecific antibody produced in escherichia coli

HIGHLIGHTS

  • who: Aaron T. Wecksler et al. from the Inc, South San Francisco, CA, USA have published the research work: Bioprocess Development and Characterization of a 13C-Labeled Hybrid Bispecific Antibody Produced in Escherichia coli, in the Journal: Antibodies 2023, 12, x FOR PEER REVIEW of /2023/
  • what: Unlike previous attempts to generate isotopically mAbs the authors provide an industry-relevant high cell density process that yielded >99% 13 C-incorporation using 13 C-glucose and 13 This work is intended to provide a framework for producing full-length of which half are isotopically to study . . .

     

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