Biocatalytic enantioselective synthesis of atropisomers

HIGHLIGHTS

  • who: Olivia F. B. Watts and colleagues from the University of Bristol, Explore Bristol Research have published the Article: Biocatalytic Enantioselective Synthesis of Atropisomers, in the Journal: (JOURNAL) of August/31,/2022
  • what: The work has explored both (hetero)biaryl compounds displaying hindered rotation around a C-C single bond, as well as rarer types of non-biaryl atropisomeric compounds such as benzamides (C-C atropisomers),10 anilides, urea and diarylamine derivatives (C-N atropisomers),11-14 diaryl ethers (C-O),15 and diaryl sulfones (C-S).16,17
  • how: In this work . . .

     

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