HIGHLIGHTS
- who: Qixia Shen from the Sichuan University, China have published the article: Integrated genomic, transcriptomic and metabolomic analysis reveals MDH2 mutation-induced metabolic disorder in recurrent focal segmental glomerulosclerosis, in the Journal: (JOURNAL)
- how: The authors used highthroughput sequencing of both DNA and RNA from FSGS patients accompanied by rFSGS or remission after KTx and healthy controls (HCs) to identify genes that are potentially involved in susceptibility to rFSGS.
- future: Studies on rs6720 in MDH2 leading to rFSGS in a large-scale cohort are necessary to confirm the findings .
SUMMARY
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