Dynamics of ctcf and cohesin mediated chromatin looping revealed by live-cell imaging

HIGHLIGHTS

• who: Sheila Teves from the DepartmentUniversity of have published the research: Dynamics of CTCF and cohesin mediated chromatin looping revealed by live-cell imaging, in the Preprint: biorxiv of 12/Dec/2021
• what: The authors propose that the absolute quantification of the Fbn2 looped fraction may now allow calibrated inference of absolute looped fractions genome-wide, based on Micro-C . Instead, the authors show that the Fbn2 TAD most often exists in a partially extruded state formed by a few cohesins in live cells (~92%; Fig 4D), and that when the rare looped state is . . .
  

   

  

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