HIGHLIGHTS
SUMMARY
The term "ferroptosis" was first reported in 2012 and was considered to be an iron-dependent non-apoptotic cell death. One study showed that that ferroptosis was involved in doxorubicin induced cardiotoxicity and ischemiareperfusion (I/R) mediated heart failure via the Nrf2/Hmox1 pathway, another study showed that ubiquitin-specific protease 7 (USP7) was involved in the regulation of ferroptosis by activating the p53/TfR1 pathway during myocardial I/R injury. The expression patterns of FRGs in AMI were further identified based on the original gene_expression data in these datasets. The Gene Expression Omnibus . . .
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