HIGHLIGHTS
- who: Renal Fibrosis and collaborators from the Department of Nephrology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China, Department of have published the Article: Histone Acetylation and Modi fi ers in Renal Fibrosis, in the Journal: (JOURNAL)
- what: In this review, the authors summarize the role and mechanism of histone acetylation and its modifiers, HAT, HDAC and BET proteins, in the regulation of renal fibrogenesis. inhibition of HDAC activity is shown to reduce infiltration of M1 and M2a macrophages and promote their conversion to M2c macrophages, and ultimately alleviate renal fibrosis (Tseng et_al . . .
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