Erythropoietin enhances post-ischemic migration and phagocytosis and alleviates the activation of inflammasomes in human microglial cells

HIGHLIGHTS

  • who: Pardes Habib from the University Hospital RWTH Aachen, Germany have published the article: Erythropoietin Enhances Post-ischemic Migration and Phagocytosis and Alleviates the Activation of Inflammasomes in Human Microglial Cells, in the Journal: (JOURNAL)
  • what: The authors provide evidence that rhEPO not only mitigated ischemiainduced oxidative stress and pyroptosis and overall cell death but also enhanced metabolic activity, migration and phagocytosis of microglial cells.
  • how: The authors therefore decided to use 4 h of OGD as a stimulus for further experiments as this ensured a sufficient hypoxic stimulus. The authors evaluated a . . .

     

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