Design, synthesis, and evaluation of lung-retentive prodrugs for extending the lung tissue retention of inhaled drugs

HIGHLIGHTS

  • who: Jack Ayre et al. from the Cynthia Bosquillon, School of Pharmacy, Boots Science Building, University Park Nottingham, Nottingham , RD, UK. have published the article: Design, Synthesis, and Evaluation of Lung-Retentive Prodrugs for Extending the Lung Tissue Retention of Inhaled Drugs, in the Journal: (JOURNAL) of March/16,/2022
  • what: Taking into account the requirement to balance extended lung retention with a sustained concentration of the free drug, the authors report here on the initial work to evaluate a new prodrug approach for extended lung tissue retention.
  • how: The synthesized prodrugs were . . .

     

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