HIGHLIGHTS
- who: Ilya Sukhanov and collaborators from the Valdman Institute of Pharmacology, Pavlov First StPetersburg State Medical University, StPetersburg, Russia have published the article: Inhibition of PDE10A in a New Rat Model of Severe Dopamine Depletion Suggests New Approach to Non-Dopamine Parkinsonu2019s Disease Therapy, in the Journal: Biomolecules 2023, 9 of 25/Oct/2022
- what: The DDD rats presented in this study have certain advantages over corresponding mouse models of severe DA depletion. The results of this study provide strong support to previously shown evidence that the D1R agonistlike action of PDE10A inhibitors can be . . .
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