Porcine relaxin but not serelaxin shows residual bioactivity after in vitro simulated intestinal digestion—clues for the development of new relaxin peptide agonists suitable for oral delivery

HIGHLIGHTS

  • who: Lorenzo Pacini and collaborators from the Interdepartmental Research Unit of Peptide and Protein Chemistry and Biology, University of Florence, Florence, Italy have published the article: Porcine Relaxin but Not Serelaxin Shows Residual Bioactivity after In Vitro Simulated Intestinal Digestionu2014Clues for the Development of New Relaxin Peptide Agonists Suitable for Oral Delivery, in the Journal: (JOURNAL) of 20/Dec/2022
  • what: This study was designed to provide additional insight into the existing knowledge on the feasibility of oral administration of 2 RLX molecules used previously for therapeutic purposes, namely serelaxin and purified porcine RLX (pRLX . . .

     

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