Tertiary lymphoid structures are critical for cancer prognosis and therapeutic response

HIGHLIGHTS

  • who: Qianqian Zhang and Suhui Wu from the Yale University, United States have published the paper: Tertiary lymphoid structures are critical for cancer prognosis and therapeutic response, in the Journal: (JOURNAL)
  • what: By leveraging this information, the authors describe how TLSs can be used to predict clinical outcomes and immunotherapeutic responses and manipulate anticancer immune_responses in a targeted manner.
  • future: A detailed analysis of the expression of immune checkpoint molecules in tumor-infiltrating immunoregulatory cells and the study of individual TLSs during tumor progression are important future directions. Future work comparing the TLS . . .

     

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