Beta-3 adrenergic receptor overexpression reverses aortic stenosis-induced heart failure and restores balanced mitochondrial dynamics

HIGHLIGHTS

  • who: Andru00e9s Pun-Garcu00eda from the Departamento Farmacologu00eda, Facultad Farmacia, ERI, Universitat Valu00e8ncia, Burjassot, Spain have published the article: Beta-3 adrenergic receptor overexpression reverses aortic stenosis-induced heart failure and restores balanced mitochondrial dynamics, in the Journal: (JOURNAL)
  • what: C57BL/6 J wildtype (WT) mice and the following transgenic lines on the C57BL/6 J genetic background were used in this study, and all experiments were conducted with adult males. The authors have shown that AS-induced LVH and HF in mice are prevented by u03b23AR overexpression achieved by two strategies: constitutive myocardial-specific . . .

     

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