Structural basis for directional chitin biosynthesis

HIGHLIGHTS

• who: from the (UNIVERSITY) have published the Article: Structural basis for directional chitin biosynthesis, in the Journal: (JOURNAL) of 17/08/2022
• what: The authors report five cryo-electron microscopy structures of a chitin synthase from the devastating soybean root rot pathogenic oomycete Phytophthora sojae (PsChs1). The authors report five cryo-electron microscopy (cryo-EM) structural snapshots of PsChs1, which provide not only a mechanistic understanding of chitin biosynthesis at the atomic level but also a structural basis for the rational design of CHS-targeting inhibitors.

SUMMARY

The key reactions of . . .

 



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