M5c-dependent cross-regulation between nuclear reader alyref and writer nsun2 promotes urothelial bladder cancer malignancy through facilitating rabl6/tk1 mrnas splicing and stabilization

HIGHLIGHTS

• who: Ning Wang from the the bladder (UCB) derived from Sun Yat-sen University have published the research work: m5C-dependent cross-regulation between nuclear reader ALYREF and writer NSUN2 promotes urothelial bladder cancer malignancy through facilitating RABL6/TK1 mRNAs splicing and stabilization, in the Journal: (JOURNAL) of 19/09/2022
• what: By applying patient-derived organoids model and orthotopic xenograft mice model the authors demonstrate that enhances proliferation and invasion of UCB cells in an m5C-dependent manner. The authors demonstrate that m5C regulators are predominantly upregulated in UCBs from Sun Yat-sen University . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.