Angiotensin at2 receptor stimulation alleviates collagen-induced arthritis by upregulation of regulatory t cell numbers

HIGHLIGHTS

  • who: Bettina Sehnert from the Hannover Medical School, Germany Comenius University, Slovakia have published the article: Angiotensin AT2 Receptor Stimulation Alleviates Collagen-Induced Arthritis by Upregulation of Regulatory T Cell Numbers, in the Journal: (JOURNAL)
  • what: The authors provide evidence that C21 exerts beneficial effects on clinical manifestations and histopathology in CIA, a commonly used mouse model to study RA . The study demonstrates that selective stimulation of the endogenous AT2R pathway by the non-peptidic Compound 21 has beneficial clinical and histological effects on CIA.
  • how: Cells were measured on a FACSCalibur flow . . .

     

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