Structure of the malaria vaccine candidate pfs48/45 and its recognition by transmission blocking antibodies

HIGHLIGHTS

  • who: Kuang-Ting Ko from the (UNIVERSITY) have published the paper: Structure of the malaria vaccine candidate Pfs48/45 and its recognition by transmission blocking antibodies, in the Journal: (JOURNAL) of 24/05/2022
  • what: The authors demonstrate that antibodies which bind across this molecule can be transmission-blocking. This analysis shows that no single angle fits most closely to the SAXS data, with a broad range of models, with interdomain angle 56u00b0 from 93u00b0, all fitting with a lower u03c72 than any of the crystal_structures. The authors the authors removed all N-methyl and . . .

     

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