Klotho ameliorates podocyte injury through targeting trpc6 channel in diabetic nephropathy

HIGHLIGHTS

  • who: Xingmei Yao and colleagues from the Department of Nephrology, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China have published the Article: Klotho Ameliorates Podocyte Injury through Targeting TRPC6 Channel in Diabetic Nephropathy, in the Journal: Journal of Diabetes Research of 18/04/2022
  • what: The research demonstrated that KL defended against hyperglycemia-induced podocyte injury in DN via suppressing TRPC6, which provided novel mechanistic insights for the role of KL in DN.
  • how: These results indicated that KL could protect podocytes from injury and apoptosis thereby improving glomerular filtration function . . .

     

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