Hepatitis b virus dna integration as a novel biomarker of hepatitis b virus-mediated pathogenetic properties and a barrier to the current strategies for hepatitis b virus cure

HIGHLIGHTS

  • who: Romina Salpini1 and colleagues from the Nanjing Medical University, China have published the paper: Hepatitis B virus DNA integration as a novel biomarker of hepatitis B virus-mediated pathogenetic properties and a barrier to the current strategies for hepatitis B virus cure, in the Journal: (JOURNAL)
  • what: By analyzing the whole exome of hepatocytes, this study has shown that HBV-DNA integration occurs not only in a notable proportion of patients with high HBV-DNA levels (55.6%), but also at significant frequency in patients with low (25%) and moderate viremia (14.3%), despite . . .

     

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