Serum metabolic traits reveal therapeutic toxicities and responses of neoadjuvant chemoradiotherapy in patients with rectal cancer

HIGHLIGHTS

• who: Hongmiao Wang from the Serum metabolic traits in response to nCRT in LARC patients In this study, we recruited , patients with clinical, and/or N + rectal cancer diagnosed from Fudan University Shanghai Cancer Center (FUSCC), Shanghai, ChinaAll enrolled patients were treated with the standard neoadjuvant chemoradiotherapy (nCRT) protocol followed by total mesorectal excision surgery (see Methods section). The detailed information on the clinical cohort is listed in Supplementary Table, . To investigate the metabolic dynamics over the course of nCRT, serum samples for each patient were collected at the following time points: before nCRT (Time, ), at the . . .
  

   

  

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